Figure 1

Application examples of the GeneHopper database. (a) A within-species search for cDNA clones from the Research Genetics human cDNA library corresponding to 50 marker genes to distinguish acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) that were identified by screening 72 leukemia patients on HuGeneFL Affymetrix arrays [33]. (b) A between-species search with genes deregulated in human muscular dystrophies, based on four HuGeneFL arrays [23], to compare to results of dystrophic mouse muscle analysis on MG-U74Av2 Affymetrix arrays [24]. (c) Comparison of results from two different technologies used to analyze expression in mouse livers. Accession numbers corresponding to SAGE tags were linked to probes on the Mu11KB Affymetrix array [27]. These searches were carried out using UniGene builds Hs.149 and Mm.105.