Figure 8From: A new non-linear normalization method for reducing variability in DNA microarray experimentsBox plots for R/G log-ratios by print tip. A strong print-tip bias can be seen after (a) global lowess or qspline but (b) is partially removed after scaling the R and G signals within each print-tip group before qspline normalization. Normalizing for (c) the spatial signal bias and (d) scaled print-tip lowess show more comparable tip distributions.Back to article page