Figure 2From: The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenasesA structural model of the DSBH core of the 2OG-Fe(II) dioxygenase superfamily. This is based on the Emericella nidulans isopenicillin N synthase structure (PDB:1ips). The side chains of the amino acid residues implicated in catalysis and in substrate binding are shown (see text) and the Fe(II) ion is indicated by a red circle.Back to article page