Evidence for symmetric chromosomal inversions around the replication origin in bacteria

Table 2 Whole-genome protein-level comparisons

Organism 1	Organism 2	Total	Matches	Probability^*
		matches	within
			10%
			diagonal
Top matches
V. cholerae	E. coli	1,797	369	3.2 ± 10^-40
V. cholerae (rev)	E. coli	1,797	441	2.3 ± 10^-70
V. cholerae	V. cholerae	701	145	3.6 ± 10^-17
V. cholerae (rev)	V. cholerae	701	70	0.52
E. coli	E. coli	1,985	286	3.6 ± 10^-10
E. coli (rev)	E. coli	1,985	210	0.20
Recent duplications^†
V. cholerae	V. cholerae	195	60	1.0 ± 10^-15
V. cholerae (rev)	V. cholerae	195	26	8.4 ± 10^-4

^*Statistical significance was estimated as described in the text. ^†Best match to another V. cholerae ORF versus any other complete genome.

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