Fig. 7.

Model for the transmission of variant genomes. This model suggests that genomes encoding amino acids under strong selection pressure (such as P323 in this case) have potential options for growth and transmission of viral populations via either consensus viral genomes with P323 (cyan) and L323 (red) present in minor variant genomes or in equilibrium, or where L323 is dominant in the viral genome sequence and P323 present at a minor variant level. Given the potential strong selection pressure on position 323, the time post infection transmission occurs is crucial in determining which variant becomes dominant viral genome sequence. This figure was created using Biorender.com