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Fig. 3 | Genome Biology

Fig. 3

From: Network propagation-based prioritization of long tail genes in 17 cancer types

Fig. 3

Biological enrichment results for UMGs at cancer type and pan-cancer levels. a UMGs uncover known and novel associations between cancer types and biological pathways. Enrichment analyses are performed for each cancer type’s combined list of UMGs and drivers. Shown results correspond to significant pathway and molecular function associations exclusively uncovered by UMGs. b Pan-cancer analysis of all 230 UMGs allows for the identification of biological pathways, processes, and functions strongly associated with UMGs (in red) that suggests potential therapeutic targets. c A similar analysis to b on clusters of KEGG mega-pathways uncover disease-disease and disease-infection associations pertaining to UMGs

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