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Table 2 Expected occurrences of multimeric motifs in human genome

From: Global properties of regulatory sequences are predicted by transcription factor recognition mechanisms

 

1 TF

2 TF

3 TF

4 TF

5 TF

6 TF

Possible combinations

1600

1.3 × 106

2.1 × 109

3.3 × 1012

5.2 × 1015

8.4 × 1018

Percent that cooperate (%)

100

3

0.09

0.0027

8.1 × 10−5

2.4 × 10−6

Expected number of motifs

1600

38000

1.8 × 106

8.8 × 107

4.3 × 109

2.0 × 1011

Effective motif length (based on IC)

6

8

12.25

16.25

21

25.5

Individual motif hits in human genome

7.3 × 105

4.6 × 104

1.3 × 102

0.49

0.00068

1.3 × 10−6

Total motif hits in human genome

1.2 × 109

1.8 × 109

2.3 × 108

4.4 × 107

2.9 × 106

2.8 × 105

  1. Columns indicate number of TFs in multimeric motifs