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Fig. 3 | Genome Biology

Fig. 3

From: The Pseudomonas aeruginosa accessory genome elements influence virulence towards Caenorhabditis elegans

Fig. 3

Association between protein-coding genes of P. aeruginosa and bacterial virulence. a (Top panel) median survival of adult C. elegans worms exposed to a collection of 52 P. aeruginosa strains (with 95% confidence interval, C.I.). The strains are ordered from high to low virulence (left to right) and aligned with the matrixes below middle and bottom left panels: Gene presence/absence matrix for HVA genes (middle) and LVA genes (bottom). Gene presence is indicated with black squares and absence with white squares. Genes (rows) are aligned with the corresponding p values. Middle and bottom right panels: Association statistics (p value of MW and LR tests) for the HVA and LVA genes, shown as |log10(pval)|. b, c Associated genes present in the strain PA14 (b) or ATCC27853 (c). Gene loci are plotted against the association statistic (p value of MW test), shown as |log10(pval)|. Loci are colored according to the directionality of the gene-virulence association (gray: positively associated; red: negatively associated; yellow: p value equals zero). Horizontal dashed lines demarcate a significance threshold (p < 0.01)

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