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Table 1 Characteristics of the four main cohorts at the time of blood draw. All entries represent averages with standard deviations unless otherwise indicated

From: Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies

 

Phenotypes

DNA methylation

RNA-seq

LL

LLS

NTR

RS

LL

LLS

NTR

RS

LL

LLS

NTR

RS

n = 761

n = 790

n = 1866

n = 768

n = 741

n = 712

n = 735

n = 762

n = 740

n = 579

n = 882

n = 628

Age

45 ± 13

58 ± 8

37 ± 14

68 ± 6

46 ± 13

59 ± 7

40 ± 15

68 ± 7

45 ± 13

59 ± 7

38 ± 15

69 ± 6

Sex (% male)

0.42

0.48

0.33

0.43

0.42

0.48

0.35

0.43

0.42

0.47

0.35

0.43

Smoking (% current)

0.15

0.11

0.19

0.10

0.15

0.12

0.19

0.10

0.15

0.13

0.18

0.09

BMI

25 ± 4

25 ± 4

24 ± 4

28 ± 4

25 ± 4

25 ± 3

25 ± 4

28 ± 4

25 ± 4

25 ± 3

25 ± 4

28 ± 4

Lymp (% of cells)

34 ± 8

29 ± 7

35 ± 9

36 ± 8

35 ± 7

29 ± 7

35 ± 9

36 ± 8

34 ± 8

29 ± 7

35 ± 9

36 ± 8

Mono (% of cells)

9 ± 2

5 ± 2

8 ± 3

7 ± 2

9 ± 2

6 ± 2

8 ± 3

7 ± 2

9 ± 2

6 ± 2

9 ± 3

7 ± 2

Gran (% of cells)

57 ± 8

63 ± 7

56 ± 9

57 ± 8

57 ± 8

63 ± 7

57 ± 9

57 ± 9

57 ± 8

63 ± 7

56 ± 9

57 ± 8

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Genome Biology

ISSN: 1474-760X

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