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Fig. 2 | Genome Biology

Fig. 2

From: The majority of A-to-I RNA editing is not required for mammalian homeostasis

Fig. 2

Peripheral blood and hematopoietic parameters of Adar1E861A/E861AAdarb1−/− mice. a Red blood cell counts. b Hemoglobin. c Hematocrit. d Mean corpuscular volume. e Platelet count. f Peripheral blood leukocyte numbers and lineage distribution from the indicated genotypes, C57Bl/6 = 8 (white circle); dHet (Adar1E861A/+Ifih1−/−Adarb1+/−Gria2R/R) = 8 (gray); Adar1+/+Adarb1−/− (Ifih1−/−Gria2R/R) = 3 (green); Adar1E861A/E861AAdarb1−/− (Ifih1−/−Gria2R/R) = 7 (blue), *P < 0.05, **P < 0.01. g Cellularity of the femurs, spleen, and thymus from the indicated genotypes, n = 3 per genotype. All counts were performed on peripheral blood from 12–18-week-old male animals of the indicated genotypes. Number of animals in each genotype indicated in panel a. Statistical analysis: one-way ANOVA with correction for multiple comparisons; *P < 0.05; **P < 0.01; ***P < 0.001

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