Fig. 2From: Systematic comparative analysis of single-nucleotide variant detection methods from single-cell RNA sequencing dataThe performance measurements of different variant-calling tools in high-confident coding regions for simulated data. a The flowchart showing the simulation procedure of inserting variants into the reference genome and performance assessments. b, c Performance curves showing the TPRs (b) and FDRs (c) according to the minimal read depths at inserted SNV loci in high-confident coding regions. d Boxplots showing F-scores of different tools with read depths ≥ 10. e The flowchart showing the simulation procedure based on RSEM. f, g Performance curves showing the TPRs (f) and FDRs (g) according to the minimal read depths at inserted SNV loci in high-confident coding regions using RSEM simulationBack to article page