Fig. 3

Most methods tend to infer the association DC network. Performance of 11 DC inference methods and 2 co-expression methods (highlighted in grey) across 812 different simulations with approximately 500 observations sampled. Performance is quantified using the F1 score and is computed for the three different representations of DC networks: direct, influence, and association. Methods are sorted based on the sum of their F1 scores across all simulations and truth networks. For co-expression methods, the difference of co-expression networks generated separately in each condition was taken as the DC network