Fig. 3
From: DeepCRISPR: optimized CRISPR guide RNA design by deep learning
Evaluation of DeepCRISPR for off-target profile prediction. a Comparison of sgRNA off-target profile predictions in a classification schema for various datasets, i.e., 293-related cell types and K562 cell line with a maximum of six mismatches. The performance was evaluated with ROC-AUC. b Comparison of sgRNA off-target profile predictions in a classification schema for various datasets, i.e., 293-related cell types and K562 cell line with a maximum of six mismatches. The performance was evaluated with PR-AUC. c Comparison of sgRNA off-target profile predictions in a regression schema for various datasets, i.e., 293-related cell types and K562 cell line with a maximum of six mismatches. The performance was evaluated with Spearman correlation. d Comparison of sgRNA off-target profile predictions in a regression schema for various datasets, i.e., 293-related cell types and K562 cell line with a maximum of six mismatches. The performance was evaluated with weighted Spearman correlation