Fig. 2
From: DotAligner: identification and clustering of RNA structure motifs
Comparison of RNA structure alignment quality as a function of sequence identity. BRAliBase 2.1 reference RNA structure alignments were submitted to five different pairwise alignment algorithms, including the Needleman–Wunsch sequence-only alignment algorithm. Top: The total number of surveyed alignments as a function of pairwise sequence identity. The Matthews correlation coefficient (MCC), the difference in the structural conservation index (Δ-SCI) and RNAdistance calculated topological edit distance between the RNAalifold consensus of the computed alignment and the reference BRAliBase 2.1 alignment consensus are compared in the lower three plots. MCC Matthews correlation coefficient, SCI structural conservation index