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Fig. 1 | Genome Biology

Fig. 1

From: The oncogenic role of circPVT1 in head and neck squamous cell carcinoma is mediated through the mutant p53/YAP/TEAD transcription-competent complex

Fig. 1

circPVT1, SMG7, and RPN2 expression in the HNSCC cancer data set. ad Bioinformatic analysis of PVT1 and circPVT1 amplification using the HNSCC cancer data set provided by The Cancer Genome Atlas. a Chromosomal intervals of the PVT1 gene in tumor and non-tumoral samples. The peak related to circPVT1 is indicated by an oval (Wilcoxon rank sum test, p < 0.05). b Chromosomal intervals of the PVT1 gene in tumor samples (divided into mut-p53 and wt-p53) and in non-tumoral samples. The peak related to circPVT1 is indicated by an oval (Wilcoxon rank sum test, p < 0.05). c Chromosome interval containing circPVT1 in tumor and non-tumoral samples. d Chromosome interval containing circPVT1 in tumor (divided into mut-p53 and wt-p53) and non-tumoral samples. e Chromosome interval containing SMG7 in tumor and non-tumoral samples. f Chromosome interval containing SMG7 in tumor (divided into mut-p53 and wt-p53) and non-tumoral samples. g Chromosome interval containing RPN2 in tumor and non-tumoral samples. h Chromosome interval containing RPN2 in tumor (divided into mut-p53 and wt-p53) and non-tumoral samples. MUT p53 mutation, N non-tumoral, T tumoral, WT wild type

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