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Table 3 Comparison between experimentally measured and computationally predicted antibiotics susceptibility profiles

From: MICRA: an automatic pipeline for fast characterization of microbial genomes from high-throughput sequencing data

Antibiotic Class Exp. MICRA Kuznetsov et al. ResFinder
Ampicillin Beta-lactam, penicillins R R* ND R**
Amoxicillin Beta-lactam, penicillins R R* ND R**
Piperacillin Beta-lactam, penicillins R R* S R**
Cefuroxim Beta-lactam, cephalosporins R R* ND R**
Cefoxitin Beta-lactam, cephalosporins R R R R**
Cefotaxim Beta-lactam, cephalosporins R R* ND R**
Ceftazidim Beta-lactam, cephalosporins R R R R**
Cefpodoxime Beta-lactam, cephalosporins R R R R**
Imipenem Beta-lactam, carbapenems S S S R**
Meropenem Beta-lactam, carbapenems S S S R**
Amikacin Aminoglycoside S S S ND
Gentamicin Aminoglycoside S S S ND
Kanamycin Aminoglycoside S S S ND
Tobramycin Aminoglycoside S S S ND
Streptomycin Aminoglycoside R R R R
Ciprofloxacin Fluoroquinolone S S ND S
Norfloxacin Fluoroquinolone S R* ND S
Tetracyclin Polyketide R R R R
Nitrofurantoin Furans S S S ND
Trimethoprim/sulfamethoxazole Aminopyrimidine R R R R
Chloramphenicol Phenicol S R ND S
Fosfomycin Phosphonic acids S S R S
  1. Note that ResFinder mainly makes predictions for antibiotic classes rather than individual drugs. R resistant, S sensitive, R* not sensitive considered as a particular resistance, R** prediction for beta-lactam class, not individual drugs, ND not determined. Incorrect predictions appear in bold text