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Fig. 5 | Genome Biology

Fig. 5

From: Regulatory remodeling in the allo-tetraploid frog Xenopus laevis

Fig. 5

Pseudogenization rate has increased after hybridization. a Number of likely pseudogenes (i.e. genes having one or more pseudogene feature and no expression while their homeolog is expressed) binned by predicted date of pseudogenization event. b Pseudogenes with different (non-exclusive) pseudogene features and their sum over the years. c Left: fraction of genes that have a nonsense variant in the population. Right: fraction of mutations in coding regions that introduce a premature stop codon. d Expression of genes with and without a nonsense variant present in the population. e Distribution of predicted pseudogenization time (including one-to-one orthologs of human, mouse, and chicken) for genes with a single pseudogene feature and a tenfold lower expression than the homeolog (top), for genes with a nonsense variant present in the population of X. laevis (middle) and for genes that do not present any feature for pseudogenization and whose expression is less than twofold different between homeologs (bottom)

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