Fig. 3From: DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3AdCas9-SunTag-DNMT3A methylates the intragenic regions of KLF4 without affecting gene expression. a The percent of methylation across individual CpGs as determined using deep sequencing of amplicons in a 2.5-kb window of the KLF4 locus. The gray bar represents the guide RNA binding site. b The fold change relative to dCas9SunTag + scFvDNMT3A1 as measured by quantitative PCR for KLF4 expressionBack to article page