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Fig. 6 | Genome Biology

Fig. 6

From: Genome-wide mapping of transcriptional enhancer candidates using DNA and chromatin features in maize

Fig. 6

Average profiles of the enhancer candidates in (a) V2-IST and (b) husk. Average signal intensities of DNase I hypersensitivity, H3K9ac enrichment in RPM and DNA methylation levels in methylation frequency at DHSs and their 1-kb flanking regions. DHSs were scaled to equal size. Prior to calculation of the average, all the DHSs were oriented based on H3K9ac enrichment intensity values 300 bp away from the DHS boundaries; the sides with higher H3K9ac enrichment were defined as 3' end. The profiles show a clear preferential enrichment of H3K9ac 3’ of the DHSs and high levels of DNA methylation (CG and CHG context) around the DHSs and H3K9ac-enriched regions. The level of mCHH is low throughout the regions with a slight increase at the 5’ side of DHSs

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