A statistical framework for analyzing deep mutational scanning data

Table 1 Datasets analyzed with Enrich2

Target	Assay	Replicates	Time points	Scored variants	Reads (millions)	Run time (h:min)	Reference
BRCA1	Phage display	6	6	11,530	423	6:23	[4]
BRCA1	Yeast two-hybrid	6	4	17,165	306	6:23	[4]
E4B	Phage display	2	4	158,939	67	2:27	[14]
Neuraminidase	Growth in cell culture	6^a	2	6834	24	0:08	[30]
C2 domain	Phage display	3	3	1081	48	1:17	This work
WW domain	Phage display	2^b	4	48,183	33	10:32	[1]

^aThree replicate selections each of two experimental conditions, with a shared input library
^bResequencing of the same selection

ISSN: 1474-760X