Fig. 3From: DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases Manhattan plot depicting the –log10(P values) and effect direction (respectively to CRP) of the associations between the 58 replicated CpG sites and each cardiometabolic phenotype, adjusted for age, sex, BMI, cell distributions, technical covariates, and smoking. The dotted lines indicate the Bonferroni threshold of 9.58 × 10−5 for significanceBack to article page