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Fig. 3 | Genome Biology

Fig. 3

From: Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humans

Fig. 3

OAS-introgressed haplotypes show multiple signatures of positive selection. a Normalized absolute iHS scores (y-axis) across SNPs in the CEU sample. Dashed lines represent the 95th percentile of iHS calculated genome-wide across all SNPs (gray) and all NLS SNPs (black). b The H D/A statistic in CEU (y-axis). Dashed line indicates the 99th percentile of H D/A calculated across 1000 simulations. c Fst calculated between CEU and all East Asian populations from the 1000 Genomes projects (y-axis). Dashed lines indicate the 95th (gray) and 99th (black) genome-wide percentiles of Fst. Similar results are obtained when comparing any other European population against East Asians (Additional file 2: Table S5). d Tajima’s D (y-axis) calculated for CEU and YRI samples. Dashed lines indicate the 1st and 99th genome-wide percentiles of Tajima’s D

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