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Fig. 1 | Genome Biology

Fig. 1

From: Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms

Fig. 1

Discovery of aVMPs in whole blood of 3295 individuals. a Flow chart of the different sets of CpGs identified in the current study, in cis and in trans. QC quality control. b Shannon entropy (y-axis) against age (x-axis) in 3295 individuals. c Volcano plot of the DNA methylation change in average (x-axis) against the change in variability (y-axis). d Examples of the three classes of aVMPs identified: aVMPs without a change in average (constant-aVMPs, cg21752383), aVMPs with a gain in DNA methylation (gain-aVMPs; cg01873886), and aVMPs with a loss in methylation (loss-aVMPs; cg14127336)

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