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Table 2 MEME/TOMTOM agnostic motif analysis

From: Novel regional age-associated DNA methylation changes within human common disease-associated loci

Hypomethylated motif 1

SPDEF_DBD_3

Hypomethylated motif 2

FOXC1_DBD_1

 

ONECUT3_DBD

 

UP00037_1 (Zfp105_primary)

 

UP00097_2 (Mtf1_secondary)

 

ONECUT1_DBD

Hypomethylated motif 3

SP8_DBD

 

SP1_DBD

 

SP3_DBD

 

KLF14_DBD

 

Klf12_DBD

 

KLF16_DBD

 

SP4_full

 

UP00011_2 (Irf6_secondary).

Hypermethylated motif 1

SPDEF_DBD_3

  1. Enrichment for defined TFBS within hypomethylated and hypermethylated a-DMRs via MEME/TOMTOM motif analysis [38]