Fig. 7
From: MUFFINN: cancer gene discovery via network analysis of somatic mutation data
Networks of candidate cancer genes predicted by MUFFINN and their direct neighbors on HumanNet. Networks are visualized using Cytoscape for a HDAC1, b APEX1, c FN1, and d PPM1A. Edge thickness represents edge weight (likelihood of two genes being involved in the same pathway) by HumanNet and node color scale represents the mutational frequency of each gene, where higher mutation frequency is indicated as more reddish color. Genes with no mutation occurrence at all are indicated as an empty node. The subjected candidate genes, their neighboring candidate genes, and other genes are represented as hexagonal, rectangular, and circular nodes, respectively. Genes for each enriched pathway are grouped by a curved box