Table 3 Protein-related fields reported by the VEP
Property | Description |
|---|---|
Protein ID | Ensembl stable identifier for affected protein product |
RefSeq ID | NCBI RefSeq identifier for affected protein |
SWISSPROT ID | Manually curated protein identifier from UniProt |
TrEMBL ID | Automatically generated identifier from UniProt |
UniParc ID | Combined protein identifier from UniProt |
Protein coordinates | Coordinates of input variant in protein product |
Codons | Reference and alternative codons as generated by input variant |
Amino acids | Reference and alternative amino acids as generated by input variant |
SIFT | SIFT pathogenicity prediction and score |
PolyPhen | PolyPhen-2 pathogenicity prediction and score |
Protein domains | Protein domains overlapping input variant |
HGVS | HGVS notations for input variant relative to the protein sequence |