Skip to main content

Table 2 Number of SNV and short insertion/deletion mutations in the sequenced samples

From: A comprehensive survey of the mutagenic impact of common cancer cytotoxics

Treatment

n

SNV

Insertion

Deletion

Mean ± SD

Mean ± SD

Mean ± SD

None (starting clone)

1

0

0

0

Mock

4

47 ± 20

4.5 ± 1.3

3.0 ± 0.8

Cisplatin

3

812 ± 193

49.0 ± 15.0

83.0 ± 21.2

Cyclophosphamide

3

254 ± 50

3.0 ± 1.7

5.0 ± 1.7

Hydroxyurea

3

74 ± 9

4.7 ± 1.5

3.7 ± 1.2

Gemcitabine

3

57 ± 31

2.3 ± 2.1

3.0 ± 1.7

5-fluorouracil

3

50 ± 16

3.0 ± 1.0

2.7 ± 1.5

Etoposide

3

95 ± 15

3.7 ± 1.2

6.7 ± 4.2

Doxorubicin

3

44 ± 15

3.3 ± 0.6

4.0 ± 4.6

Paclitaxel

3

64 ± 10

1.0 ± 1.0

3.0 ± 0.0