Table 1 Description of the simulation parameters
From: Pooling across cells to normalize single-cell RNA sequencing data with many zero counts
Symbol | Description |
|---|---|
θ j | Cell-specific bias for cell j |
λ is | Expected number of transcripts for gene i in subpopulation s |
Ï• is | DE fold change for gene i in subpopulation s |
λ i0 | Baseline expectation for the number of transcripts |
| Â | (i.e., without DE) for gene i |
φ i | NB dispersion for gene i |
Ï• s | DE fold change for all upregulated genes in subpopulation s |
G | Number of unique DE genes in each subpopulation |
p s | Proportion of DE genes that are upregulated in subpopulation s |