Fig. 1

Catalogue of lncRNAs in human neocortex development. a Schematic of neocortex tissue dissection, poly(A) and total RNA-seq library prep, and computational pipeline for lncRNA annotation and quantification. b Numbers of expressed (left) and differentially expressed (right; DESeq2, FDR <0.01) mRNAs, lncRNAs, and TUCPs during neocortex development in bulk tissues. Stringent references omit novel single exon transcripts. c Breakdown of expressed (left) and differentially expressed (right) lncRNAs based on genomic orientation relative to mRNAs. d Maximum expression levels of transcripts described in the Full and Stringent references derived from Poly(A) selection RNA-seq, across all samples. TPM, Transcripts per Million