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Fig. 4 | Genome Biology

Fig. 4

From: Beyond comparisons of means: understanding changes in gene expression at the single-cell level

Fig. 4

Posterior estimates of model parameters based on random permutations of the mESC cell-cycle data set. For a single permuted data set: a Empirical distribution of posterior medians for mRNA content normalizing constants \(\phi _{j_{p}}\) across all cells. b Empirical distribution of posterior medians for gene-specific expression rates μ ip across all genes. c Empirical distribution of posterior medians for gene-specific biological over-dispersion parameters δ ip across all genes. d As an average across ten random permutations. Upper diagonal panels compare estimates for gene-specific expression rates μ ip between groups of cells. Lower diagonal panels compare gene-specific biological over-dispersion parameters δ ip between groups of cells

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