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Fig. 4 | Genome Biology

Fig. 4

From: OncoNEM: inferring tumor evolution from single-cell sequencing data

Fig. 4

Dependence of OncoNEM’s clustering solution on Bayes factor threshold ε. This figure shows the V-measure and the number of clones of the OncoNEM solution as a function of ε for various simulation scenarios. Every line corresponds to one data set of the method comparison study. Lines are color coded by parameter setting for the varied simulation parameter. In all simulation scenarios, the number of clones is largely independent of ε, unless it is set to be unreasonably small (ε<5). The threshold ε used throughout the simulation and case studies is 10 (dashed line), and thus well within the stable range

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