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Fig. 5 | Genome Biology

Fig. 5

From: P16-specific DNA methylation by engineered zinc finger methyltransferase inactivates gene transcription and promotes cancer metastasis

Fig. 5

Migration and invasion assays carried out with cell lines stably transfected with the P16-dnmt pTRIPZ vector in vitro. a, b Results of Transwell migration assays for GES-1 and BGC823 cell lines following 48-h and 36-h incubation, respectively; c, d Results of Matrigel invasion assays for GES-1 and BGC823 cell lines following 108-h and 96-h incubation, respectively; the average cell number and s.d. are displayed (Right). Dox (+), with 0.25 μg/mL doxycycline treatment; Dox (−), without doxycycline treatment. These experiments were independently repeated in triplicate

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Genome Biology

ISSN: 1474-760X

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