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Table 7 Top 13 SEED subsystems for genes identified uniquely by subtractive assembly, and which passed a Wilcoxon rank-sum test with FDR correction, in the T2D cohort

From: Subtractive assembly for comparative metagenomics, and its application to type 2 diabetes metagenomes

Rank

SEED subsystem

Number of genes

1

Peptidoglycan biosynthesis

138

2

Fructooligosaccharides and raffinose utilization

103

3

Multidrug resistance efflux pumps

100

4

Cell division

89

5

Sialic acid metabolism

80

6

Gene cluster associated with Met-tRNA formyltransferase

77

7

Glycerolipid and glycerophospholipid metabolism

73

8

DNA repair, bacterial

73

9

Choline and bataine uptake and betaine biosynthesis

73

10

Murein hydrolases

72

11

Maltose and maltodextrin utilization

66

12

Beta-glucoside metabolism

62

13

Lactose and galactose uptake and utilization

62