Fig. 6
From: An ensemble approach to accurately detect somatic mutations using SomaticSeq
F 1 scores of SomaticSeq and the individual tools in in silico titration. Color legends are shown in Fig. 3. On the x-axes, the subscript denotes the expected VAF as a percentage, i.e., N 0 T 50 means the normal has VAF = 0 % (i.e., pure normal) and the tumor has VAF = 50 %. N 2.5 T 15 represents a challenging data set where VAF = 2.5 % for normal and VAF = 15 % for tumor, i.e., 5 % of the normal sample is contaminated with tumor tissues and 30 % of the tumor sample is contaminated with normal tissues. a SNV results. b Indel results