Skip to main content
Figure 4 | Genome Biology

Figure 4

From: Most partial domains in proteins are alignment and annotation artifacts

Figure 4

Structural partials.(A) The structure of [PDB:1H12] with secondary structures for CATH domain 1.10.580.10 (58 to 274, 385 to 410) highlighted in red (helix) and yellow (strand), and secondary structures for the CATH domain 1.10.230.10 (275 to 384) that aligns with the partial [Pfam:PF00285] region of [UniProt:Q98FC2], highlighted in cyan (helix) and salmon (coil). (B) The structure of 2NZW, the most abundant putative partial ([Pfam:PF00852]), with residues 180 to 330 highlighted. (C) The structure of 2ZXC, a representative of the PF04734 PfamA family. The putative partial analysis identifies a shorter alignment in the first 200 residues of the PfamA family, and VAST+ annotates a domain from residues 1 to 292, which are highlighted.

Back to article page