Figure 6
From: Domain atrophy creates rare cases of functional partial protein domains
C-terminal end-bounded atrophy: Ral-GTPase-activating protein domain. The reference protein human Rap1-GAP and its interaction with Rap1B (green) bound to GDP (magenta) (PDB: 3BRW) is shown. The dimerisation domain (grey) is not involved in interaction with Rap1B. The region of atrophy of rat RapGAP domain mapped onto the reference structure is shown in orange (residues 301-414). The atrophied catalytic domain (blue) retains residues involved in catalysis or protein-interaction (grey sticks).