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Figure 3 | Genome Biology

Figure 3

From: Whole genome bisulfite sequencing of cell-free DNA and its cellular contributors uncovers placenta hypomethylated domains

Figure 3

Methylome of ccf DNA isolated from pregnant plasma. (a) Cytosine methylation in non-pregnant and pregnant ccf DNA for CpG, CHG, and CHH contexts are shown. P values were calculated using a Wilcox rank sum test. (b) Methylation of all cytosines located within the DMRs hypermethylated in placenta tissue relative to non-pregnant ccf DNA. The y-axis (density) is the defined as the proportion of CpG sites at a given methylation level. (c) Methylation of all cytosines located within the DMRs hypermethylated in non-pregnant ccf DNA relative to placenta tissue. The y-axis (density) is the defined as the proportion of CpG sites at a given methylation level.

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Genome Biology

ISSN: 1474-760X

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