Coverage performance and metrics. (a) Coverage depth diagram. (b) Coverage depth data for G1/0 and G2/M single cells. (c) Coverage breadth diagram. (d) Coverage breadth data for exome region of G1/0 and G2/M single cells compared to previous studies using SNS  and MALBAC (Ni et al. ). Error bars show SEM. (e) Coverage uniformity diagram. (f) Coverage depth distribution for sites with low coverage in G1/0 and G2/M single cells. (g) Lorenz curves of coverage uniformity, showing values for perfect coverage, millions of SKN2 reference cells, Nuc-Seq single cell , single cells from G1/0 and G2/M distributions, and SNS cell . (h) Capture performance of sequence reads across exons in the KRT76 locus for three single cells.