Skip to main content
Figure 1 | Genome Biology

Figure 1

From: A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies

Figure 1

Marker call rates on the Y-chromosome. Distribution of call rates for 416 Y-chromosome markers in males (red points and red line) and females (green bars). Y-chromosome markers in females are represented in light green if their respective probes sequences are predicted to cross-hybridise with multiple genomic regions. Values greater than 80 are represented by numbers. (A) For a detection threshold P <0.05 more than 50% of Y-chromosome markers show non-zero call rates (call rate >0.05%) in females, even though females do not possess a Y chromosome. (B) For a detection threshold P <10−16 only 10% of Y-chromosome markers show non-zero call rates in females. Marker call rates in males (shown in red) are not materially affected by the more stringent detection P value threshold.

Back to article page