Figure 3
From: Pancancer analysis of DNA methylation-driven genes using MethylMix
Head and neck squamous carcinoma (HNSC) methylation clustering. (A) Consensus clustering [17] in five subgroups, mutation status for four genes (NSD1, CASP8, NOTCH1 and TP53) and their corresponding methylation profiles with red indicating hypermethylation, white indicating normal methylation and blue indicating hypomethylation. (B) Overall survival for the five methylation subgroups. (C) MethylMix model for the BCL2 gene and distribution of BCL2 hypermethylation across the five HNSC subgroups.