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Figure 2 | Genome Biology

Figure 2

From: Pancancer analysis of DNA methylation-driven genes using MethylMix

Figure 2

Clear cell renal carcinoma (KIRC) methylation clustering. (A) Consensus clustering [17] in five subgroups, correlation with pathologic M stage and binarized pathologic stage (stages 3 and 4 versus stages 1 and 2) and their corresponding methylation profiles with red indicating hypermethylation, white indicating normal methylation and blue indicating hypomethylation. (B) Overall survival for the five methylation subgroups. (C) MethylMix model for the CYTIP gene and distribution of CYTIP hypermethylation across the five KIRC subgroups.

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