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Figure 4 | Genome Biology

Figure 4

From: Global loss of DNA methylation uncovers intronic enhancers in genes showing expression changes

Figure 4

A small set of promoters are de-repressed in DKO1 cells. (A) Plot showing relative DNA methylation across the gene bodies of all RefSeq genes in HCT116 and DKO1 cells. (B) Gene expression differences in HCT116 and DKO1; log2 expression values are plotted for every gene expressed in HCT116 and/or DKO1. The orange line represents a slope of x = y. The green dots represent a group of de-repressed genes with log2(HCT116 normalized expression) <1.5 and log2(DKO1 normalized expression) >2.5.

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