Figure 3From: SubcloneSeeker: a computational framework for reconstructing tumor clone structure for cancer variant interpretation and prioritizationPredicting mutation co-localization. In cases where there are multiple viable subclone structures, we count the fraction of all structures within which two mutation events are co-localized. This fraction is the probability that the two events are present in the same subclone. One can also make a ‘co-localization call’ by declaring that two events are co-localized, if this probability is above a pre-defined threshold.Back to article page