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Table 4 Genes whose expression level correlated with methylation level of CpGs in the survival signature

From: Genome-wide DNA methylation profiles in progression to in situand invasive carcinoma of the breast with impact on gene transcription and prognosis

Gene

Probe

Gene region

P-value (methylation-expression)

Coefficient (methylation-expression)

ACAP3

cg16575694

Other

8.5E-03

−0.5

ALG8

cg04817034

Other

4.8E-02

−2.7

BLZF1

cg08729004

Other

2.6E-02

0.9

C1orf74

cg20869305

Other

5.9E-04

38.7

CBS

cg05809947

Other

5.8E-03

−4.5

CEND1

cg13749939

Other

3.5E-04

1.2

CNDP2

cg25817165

Body

1.2E-05

−1.0

COLEC11

cg04947065

Other

8.7E-03

28.9

CSNK1G2

cg12219311

Other

1.5E-02

−0.6

DIEXF

cg20869305

Other

4.5E-04

32.8

EPN3

cg13635578

Other

3.7E-02

−1.6

FCGRT

cg26225829

Other

3.6E-05

2.8

FKBPL

cg00226265

Other

2.7E-02

−1.7

IRF6

cg20869305

Other

1.4E-03

61.1

KCTD21

cg04817034

Other

1.5E-02

−1.6

LDB1

cg07130508

TSS1500

4.3E-02

5.1

MACF1

cg22174844

Body

4.1E-02

−0.9

ORM1

cg13744452

Body

3.3E-07

−13.4

ORM2

cg13744452

Other

6.6E-08

−15.1

SLC19A2

cg08729004

Other

8.2E-03

3.0

SPAG4

cg26466505

Other

4.3E-02

3.3

TALDO1

cg13749939

Other

1.5E-02

1.5

TBX5

cg16559598

TSS1500

4.3E-02

−0.3

U2AF1

cg05809947

Other

2.9E-07

−2.2

USP35

cg04817034

Body

1.4E-02

−4.0

ZNF259

cg20691428

Other

2.0E-02

−1.2

  1. Gene region reflects where the CpG is located relative to the gene, P-value reflects the strength of the correlation between methylation level and expression, and the coefficient reflects the direction of the correlation between methylation level and expression.