Figure 6

Association between LCAL expression and mutation status. (A) Significant associations between LCAL expression and mutation status. Red bars designate significant associations (false discovery rate (FDR) <0.01) across LUAD tumors and blue bars across LUSC tumors. (B) Expression levels of SCAL1 (LCAL51), measured by log₂ FPKM, for wild-type (WT; black), NFE2L2 mutant (red), KEAP1 mutant (green), and both NFE2L2 and KEAP1 mutant (blue) samples. Data points are ordered by expression levels and symbols designate cohort (squares for LUAD, circles for LUSC). Thick colored lines represent the median expression levels across each group. P-values for each mutational association are also reported (*FDR <0.05, **FDR <0.01).