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Figure 7 | Genome Biology

Figure 7

From: DNA copy number evolution in Drosophila cell lines

Figure 7

Copy number and physical interaction networks. (A) A ternary plot that displays fractions of high, normal, and low copy number genes that encode complexes in Drosophila protein-protein interaction networks. Each point corresponds to a protein complex or a cluster. Distances from the three apexes in the triangle indicate fraction of cluster members from a given copy number class. Dashed lines indicate expected portion of each copy number class based on a random distribution of S2R + cell line copy numbers. Complexes where copy number composition is significantly different from the expected ratio (P < 0.05, hypergeometric test) are filled in blue. (B-F) Protein interaction networks described and labeled in (A). Green, high copy gene products; red, low; white, normal. For (F), six proteins whose associations with the proteasome parts are not clear in the literature were omitted.

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