Figure 6
From: OrthoClust: an orthology-based network framework for clustering data across multiple species
Comparison between single-species clusters and cross-species clusters generated by OrthoClust. The number of orthologous pairs for each pair of clusters generated by K-means, hierarchical clustering or PAM (Partition Around Medoids) is counted, and the fold enrichment over a null model is calculated (Materials and methods). Pairwise overlapping of clusters generated by single-species clustering (including OrthoClust with κ = 0) results in little enrichment of orthologous pairs compared with cross-species modules generated by OrthoClust.