The evolution, impact and properties of exonic splice enhancers

Table 2 Nucleotide content of the ESE datasets

	RESCUE	PESE	ESR	Ke-ESE400	Ke-ESE	INT2	INT3	INT2.400	INT3.400
A	0.478	0.34	0.277	0.221	0.212	0.345	0.466	0.398	0.497
G	0.252	0.299	0.246	0.333	0.318	0.288	0.317	0.299	0.321
T	0.13	0.134	0.249	0.138	0.179	0.162	0.099	0.13	0.074
C	0.14	0.228	0.229	0.308	0.29	0.205	0.117	0.173	0.108
AG	0.73	0.639	0.522	0.554	0.530	0.633	0.784	0.697	0.818
GC	0.392	0.527	0.475	0.641	0.609	0.493	0.435	0.472	0.429
P	4.1e-70	3.4e-26	0.035	6.1e-08	1.e-07	1.6e-31	2.2e-39	5.3e-42	1.3e-32

P value is for a binomial test on purine content using absolute counts of nucleotides with a null of 50%. Data in bold is significant after Bonferonni correction (P <0.05/9).

ISSN: 1474-760X