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Figure 4 | Genome Biology

Figure 4

From: A computational framework for boosting confidence in high-throughput protein-protein interaction datasets

Figure 4

Predicted interfaces are enriched for SNPs in the Coev2Net predicted high-confidence MAPK network. (a) Relative distribution of PolyPhen annotated mutations at the interface and non-interface. (b) SNP (PolyPhen annotated) prevalence at the interface and non-interface. (c) Somatic mutations characterized as 'missense' preferentially fall on the interface (bottom). The white circles represent corresponding means. Error bars represent the 75% to 25% data range.

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Genome Biology

ISSN: 1474-760X

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