RIDDLE: reflective diffusion and local extension reveal functional associations for unannotated gene sets via proximity in a gene network

Table 2 Top ten OMIM diseases functionally associated with predicted targets of miR-450a

	OMIM ID	Description	RAS	FDR
*1	608161	Macular dystrophy, vitelliform, adult-onset	0.08838	0.006
*2	136880	Fundus albipunctatus	0.08833	0.006
3	212750	Celiac disease	0.08820	0.010
4	123400	Creutzfeldt-Jakob disease	0.08819	0.010
*5	258100	Oguchi disease	0.08818	0.010
*6	248200	Stargardt disease	0.08815	0.012
7	158350	Cowden disease	0.08811	0.016
8	612242	Chromosome 10q23 deletion syndrome	0.08811	0.016
9	185800	Symphalangism	0.08811	0.017
10	254780	Myoclonic epilepsy of lafora	0.08810	0.019

Starred entries indicate eye-specific diseases. FDR, false discovery rate; OMIM, Online Mendelian Inheritance in Man; RAS, RIDDLE association score.

ISSN: 1474-760X